Disulfiram effects on responses to intravenous cocaine administration
نویسندگان
چکیده
منابع مشابه
Aminergic influences on intravenous cocaine self-administration by Rhesus monkeys.
WILSON, M. C. AND C. R. SCHUSTER. Aminergic influences on intravenous cocaine self-administration by rhesus monkeys. PHARMAC. BIOCHEM. BEHAV. 2(5) 563-571, 1974. Earlier observations have demonstrated that when allowed limited daily access to cocaine, monkeys self-administer approximately the same amount of cocaine dally. Treatment with neuroleptic agents increases the frequency of this behavio...
متن کاملCholinergic influence on intravenous cocaine self-administration by rhesus monkeys.
WILSON, M. C. AND C. R. SCHUSTER. 67rolhlergic influence on intravenous cocaine self-administration by rhesus monkeys. PHARMAC. BIOCHEM. BEIIAV. 1(6) 643-649, 1973.-The effects of intramuscular administration of atropine, methylatropine and physostigmine on intravenous cocaine self-administration in the rhesus monkey were ascertained. Atropine (0.5-2.0 mg/kg) increased cocaine intake, whereas m...
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The potential for addiction is thought to be greatest when drugs of abuse reach the brain rapidly, because this produces intense subjective pleasurable effects. However, the ability of drugs to induce forms of cellular plasticity related to behavioral sensitization may also contribute to addiction. Therefore, we studied the influence of rate of intravenous cocaine delivery on its ability to ind...
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Rats self-administered i.v. delivered cocaine (0.1 mg/kg) under conditions of continuous access (session length 24 hr). Each lever press resulted in an infusion according to a fixed-ratio 1 schedule. Food was continuously available except for every third session, when the rats were food deprived, i.e., provided with only 8 g at the start of the session. After behavior stabilized, the rats were ...
متن کاملAccumbal neural responses during the initiation and maintenance of intravenous cocaine self-administration.
During a chronic extracellular recording session, animals with a history of cocaine self-administration were allowed to initiate drug seeking under drug-free conditions. Later, in the same recording session, animals engaged in intravenous cocaine self-administration. During the drug-free period, 31% of 70 accumbal neurons showed a significant increase in average firing rate in association with ...
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ژورنال
عنوان ژورنال: Drug and Alcohol Dependence
سال: 2007
ISSN: 0376-8716
DOI: 10.1016/j.drugalcdep.2006.08.016